The North Atlantic in the 16th century featured the following:
- 125 Catalogued cyclones
- 0 Estimated Intensities / 125 Unknown
- 19,423 Known Fatalities
- 409 Buildings Damaged
- 669 Buildings Destroyed
- Strongest: Unknown
- Most intense: Unknown
- Deadliest: Storm Five (1591) – 4,000 fatalities
- Most destructive: Storm One (1508) – 300 buildings affected
- Wettest: Unknown
- Highest Surge: Unknown
Storm Numbers by decade
| 1500s | 9 |
| 1510s | 4 |
| 1520s | 15 |
| 1530s | 7 |
| 1540s | 8 |
| 1550s | 19 |
| 1560s | 13 |
| 1570s | 17 |
| 1580s | 13 |
| 1590s | 20 |
Upon the surrender of the Revenge on September 1, 1591, a hurricane wiped out the prevailing Spanish fleet – one of many dreadful losses that they experienced in that year. 1591 is noted as the most active hurricane season of its time, unbeaten until 1815.